pelvic GIST treated with imatinib as neoadjuvant
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منابع مشابه
Endoscopic Hemostasis of a Bleeding Gastric Gastrointestinal Stromal Tumor (gist) with Endoloop Placement
1. Arezzo A, Verra M, Morino M. Transanal endoscopic microsurgery after neoadjuvant therapy for rectal GIST. Digestive and Liver Disease 43 (2011) 921– 924. 2. Blay JY, Bonvalot S, Casali P, et al. GIST consensus meeting panellists: Consensus meeting for the management of gastrointestinal stromal tumours. Report of the GIST Consensus Conference of 20–21 March 2004, under the auspices of ESMO. A...
متن کاملGastrointestinal Stromal Tumor of the Rectum Treated with Neoadjuvant Imatinib Followed by Transanal Endoscopic Microsurgery
The gastrointestinal stromal tumor (GIST) is a rare type of tumor that expresses CD117 oncogene that can be detected by immunohistochemistry2. The most common sites of GISTs are stomach (70%), and small intestine (20%), while rectum is comprised in only 3% of the cases5. Although a rare condition, the GIST located in the distal rectum may require an abdominoperineal resection. There is no data ...
متن کاملPreoperative imatinib for patients with primary unresectable or metastatic/recurrent gastrointestinal stromal tumor
OBJECTIVES Despite its rising popularity, reports on the use of preoperative imatinib mesylate (IM) in patients with advanced gastrointestinal stromal tumor (GIST) are limited. This study aims to explore the clinical efficacy of preoperative IM in patients with primarily unresectable or metastatic/recurrent GIST. METHODS Between September 2009 and February 2014, patients with primarily unrese...
متن کاملDramatic regression and bleeding of a duodenal GIST during preoperative imatinib therapy: case report and review
BACKGROUND Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the digestive tract. The majority of GISTs is located in the stomach. Only 3-5% of GISTs are located in the duodenum associated with an increased risk of gastrointestinal bleeding as primary manifestation. With response rates of up to 90%, but complications like bleeding due to tumor necrosis in 3%, ima...
متن کاملNeoadjuvant imatinib treatment and laparoscopic anus-preserving surgery for a large gastrointestinal stromal tumor of the rectum
BACKGROUND Resection of a gastrointestinal stromal tumor (GIST) of the rectum can be difficult because of the particular location in the pelvis, and a large rectal GIST often requires abdominoperineal resection. Recent reports demonstrate that neoadjuvant imatinib treatment improves surgical outcomes in patients with a rectal GIST, and there are only a few reports of the effectiveness of laparo...
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تاریخ انتشار 2006